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PRDM8 Antibody (N-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q9NQV8
Clone Names 100617218
Peptide ID 100617218
Additional Information
Gene ID 56978
Other Names PR domain zinc finger protein 8, 211-, PR domain-containing protein 8, PRDM8, PFM5
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name PRDM8
Synonyms PFM5
Function Probable histone methyltransferase, preferentially acting on 'Lys-9' of histone H3 (By similarity). Involved in the control of steroidogenesis through transcriptional repression of steroidogenesis marker genes such as CYP17A1 and LHCGR (By similarity). Forms with BHLHE22 a transcriptional repressor complex controlling genes involved in neural development and neuronal differentiation (By similarity). In the retina, it is required for rod bipolar and type 2 OFF-cone bipolar cell survival (By similarity).
Cellular Location Nucleus.
Tissue Location Expressed in brain, heart, skeletal muscle, testes, prostate.
Research Areas
Citations (0)

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Background

PRDM8 may be involved in transcriptional regulation.

References

Newton-Cheh, C., et al. Nat. Genet. (2009) In press :Xiao, B., et al. Curr. Opin. Struct. Biol. 13(6):699-705(2003)Jiang, G.L., et al. Histol. Histopathol. 15(1):109-117(2000)

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$ 80.00
Cat# BP16736a
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