CSDE1 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | O75534 |
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Clone Names | 100623176 |
Gene ID | 7812 |
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Other Names | Cold shock domain-containing protein E1, N-ras upstream gene protein, Protein UNR, CSDE1, D1S155E, KIAA0885, NRU, UNR |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | CSDE1 (HGNC:29905) |
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Function | RNA-binding protein involved in translationally coupled mRNA turnover (PubMed:11051545, PubMed:15314026). Implicated with other RNA- binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain (PubMed:11051545, PubMed:15314026). Required for efficient formation of stress granules (PubMed:29395067). |
Cellular Location | Cytoplasm. Cytoplasm, Stress granule. Cytoplasm, P-body |
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Provided below are standard protocols that you may find useful for product applications.
Background
CSDE1 is a RNA-binding protein. Required for internal initiation of translation of human rhinovirus RNA. May be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain.
References
Bailey, S.D., et al. Diabetes Care (2010) In press :Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)Anderson, E.C., et al. J. Gen. Virol. 88 (PT 11), 3043-3052 (2007) :Wu, C., et al. Proteomics 7(11):1775-1785(2007)
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