|Other Names||Probable palmitoyltransferase ZDHHC8, Zinc finger DHHC domain-containing protein 8, DHHC-8, Zinc finger protein 378, ZDHHC8, KIAA1292, ZDHHCL1, ZNF378|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Synonyms||KIAA1292, ZDHHCL1, ZNF378|
|Function||Palmitoyltransferase involved in glutamatergic transmission. Mediates palmitoylation of ABCA1.|
|Cellular Location||Cytoplasmic vesicle membrane; Multi-pass membrane protein|
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This gene encodes a four transmembrane protein that is amember of the zinc finger DHHC domain-containing protein family.The encoded protein may function as a palmitoyltransferase. Defectsin this gene may be associated with a susceptibility toschizophrenia. Alternate splicing of this gene results in multipletranscript variants. A pseudogene of this gene is found onchromosome 22.
Shin, H.D., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 153B (6), 1167-1172 (2010) :Pinheiro, A.P., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 153B (5), 1070-1080 (2010) :Xu, M., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. (2010) In press :Yang, W., et al. Mol. Cell Proteomics 9(1):54-70(2010)Singaraja, R.R., et al. Circ. Res. 105(2):138-147(2009)
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