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SIT1 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9Y3P8 |
|---|---|
| Clone Names | 100528309 |
| Gene ID | 27240 |
|---|---|
| Other Names | Signaling threshold-regulating transmembrane adapter 1, SHP2-interacting transmembrane adapter protein, Suppression-inducing transmembrane adapter 1, gp30/40, SIT1, SIT |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | SIT1 |
|---|---|
| Synonyms | SIT |
| Function | Negatively regulates TCR (T-cell antigen receptor)-mediated signaling in T-cells. Involved in positive selection of T-cells. |
| Cellular Location | Cell membrane; Single-pass type I membrane protein |
| Tissue Location | Specifically expressed in T- and B-cells. Present in plasma cells but not in germinal center B-cells (at protein level) Expressed in T- and B-cell lymphoma. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Negatively regulates TCR (T-cell antigen receptor)-mediated signaling in T-cells. Involved in positive selection of T-cells.
References
Chapuis, J., et al. Mol. Psychiatry 14(11):1004-1016(2009)Tedoldi, S., et al. Blood 107(1):213-221(2006)Tao, W.A., et al. Nat. Methods 2(8):591-598(2005)Tao, W.A., et al. Nat. Methods 2(8):591-598(2005)Rush, J., et al. Nat. Biotechnol. 23(1):94-101(2005)
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