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ICA1 Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q05084
Clone Names 100623145
Peptide ID 100623145
Additional Information
Gene ID 3382
Other Names Islet cell autoantigen 1, 69 kDa islet cell autoantigen, ICA69, Islet cell autoantigen p69, ICAp69, p69, ICA1
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name ICA1
Function May play a role in neurotransmitter secretion.
Cellular Location Cytoplasm, cytosol. Golgi apparatus membrane; Peripheral membrane protein Cytoplasmic vesicle, secretory vesicle membrane; Peripheral membrane protein. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Peripheral membrane protein. Note=Predominantly cytosolic. Also exists as a membrane-bound form which has been found associated with synaptic vesicles and also with the Golgi complex and immature secretory granules
Tissue Location Expressed abundantly in pancreas, heart and brain with low levels of expression in lung, kidney, liver and thyroid
Research Areas
Citations (0)

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This gene encodes a protein with an arfaptin homologydomain that is found both in the cytosol and as membrane-bound formon the Golgi complex and immature secretory granules. This proteinis believed to be an autoantigen in insulin-dependent diabetesmellitus and primary Sjogren's syndrome. Alternatively splicedvariants which encode different protein isoforms have beendescribed; however, not all variants have been fully characterized.


Jin, Y., et al. Nat. Genet. 42(7):576-578(2010)Rose, J. Phd, et al. Mol. Med. (2010) In press :Buffa, L., et al. Eur. J. Cell Biol. 87(4):197-209(2008)Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :Gordon, T.P., et al. Lupus 13(6):483-484(2004)

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$ 80.00
Cat# BP16802a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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