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USP1 Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession O94782
Clone Names 100617117
Peptide ID 100617117
Additional Information
Gene ID 7398
Other Names Ubiquitin carboxyl-terminal hydrolase 1, Deubiquitinating enzyme 1, hUBP, Ubiquitin thioesterase 1, Ubiquitin-specific-processing protease 1, USP1
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name USP1
Function Negative regulator of DNA damage repair which specifically deubiquitinates monoubiquitinated FANCD2. Also involved in PCNA-mediated translesion synthesis (TLS) by deubiquitinating monoubiquitinated PCNA. Has almost no deubiquitinating activity by itself and requires the interaction with WDR48 to have a high activity.
Cellular Location Nucleus.
Research Areas
Citations (0)

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This gene encodes a member of the ubiquitin-specificprocessing (UBP) family of proteases that is a deubiquitinatingenzyme (DUB) with His and Cys domains. This protein is located inthe cytoplasm and cleaves the ubiquitin moiety from ubiquitin-fusedprecursors and ubiquitinylated proteins. The protein specificallydeubiquitinates a protein in the Fanconi anemia (FA) DNA repairpathway. Alternate transcriptional splice variants have beencharacterized.


Barroso, E., et al. Breast Cancer Res. Treat. 118(3):655-660(2009)McWilliams, R.R., et al. Cancer Epidemiol. Biomarkers Prev. 18(9):2549-2552(2009)Cohn, M.A., et al. J. Biol. Chem. 284(8):5343-5351(2009)Cohn, M.A., et al. Mol. Cell 28(5):786-797(2007)Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)

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$ 80.00
Cat# BP16884b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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