MS4A7 Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q9GZW8 |
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Clone Names | 110617217 |
Gene ID | 58475 |
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Other Names | Membrane-spanning 4-domains subfamily A member 7, CD20 antigen-like 4, CD20/FC-epsilon-RI-beta family member 4, Four-span transmembrane protein 2, MS4A7, 4SPAN2, CD20L4, CFFM4 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | MS4A7 |
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Synonyms | 4SPAN2, CD20L4, CFFM4 |
Function | May be involved in signal transduction as a component of a multimeric receptor complex. |
Cellular Location | Membrane; Multi-pass membrane protein. |
Tissue Location | Ubiquitous expression in normal tissues. Expression is more elevated in adult liver, lung, spleen, and heart than in their fetal counterparts, and is higher in normal tissues than in the cancerous tissue or cell lines. Low levels of expression were detected in the promonocytic stage, whereas high levels of expression were detected in mature monocytes |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a member of the membrane-spanning 4Agene family, members of which are characterized by commonstructural features and similar intron/exon splice boundaries anddisplay unique expression patterns in hematopoietic cells andnonlymphoid tissues. This family member is associated with maturecellular function in the monocytic lineage, and it may be acomponent of a receptor complex involved in signal transduction.This gene is localized to 11q12, in a cluster of other familymembers. At least four alternatively spliced transcript variantsencoding two distinct isoforms have been observed. [provided byRefSeq].
References
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Gingras, M.C., et al. Immunogenetics 53(6):468-476(2001)Liang, Y., et al. Immunogenetics 53(5):357-368(2001)Liang, Y., et al. Genomics 72(2):119-127(2001)Ishibashi, K., et al. Gene 264(1):87-93(2001)
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