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CSRP3 Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P50461
Clone Names 100507012
Peptide ID 100507012
Additional Information
Gene ID 8048
Other Names Cysteine and glycine-rich protein 3, Cardiac LIM protein, Cysteine-rich protein 3, CRP3, LIM domain protein, cardiac, Muscle LIM protein, CSRP3, CLP, MLP
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name CSRP3
Synonyms CLP, MLP
Function Positive regulator of myogenesis. Plays a crucial and specific role in the organization of cytosolic structures in cardiomyocytes. Could play a role in mechanical stretch sensing. May be a scaffold protein that promotes the assembly of interacting proteins at Z-line structures. It is essential for calcineurin anchorage to the Z line. Required for stress-induced calcineurin-NFAT activation (By similarity).
Cellular Location Nucleus. Cytoplasm. Cytoplasm, cytoskeleton. Cytoplasm, myofibril, sarcomere, Z line. Note=Mainly cytoplasmic (By similarity). In the nucleus it associates with the actin cytoskeleton (Potential). In the Z line, found associated with GLRX3 (By similarity) {ECO:0000250, ECO:0000305}
Tissue Location Cardiac and slow-twitch skeletal muscles.
Research Areas
Citations (0)

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This gene encodes a member of the CSRP family of LIMdomain proteins, which may be involved in regulatory processesimportant for development and cellular differentiation. TheLIM/double zinc-finger motif found in this protein is found in agroup of proteins with critical functions in gene regulation, cellgrowth, and somatic differentiation. Mutations in this gene arethought to cause heritable forms of hypertrophic cardiomyopathy(HCM) and dilated cardiomyopathy (DCM) in humans. Alternativelyspliced transcript variants with different 5' UTR, but encoding thesame protein, have been found for this gene.


Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Zimmerman, R.S., et al. Genet. Med. 12(5):268-278(2010)Rampersaud, E., et al. Ann. Hum. Genet. 74(2):110-116(2010)Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)Moller, D.V., et al. Eur. J. Heart Fail. 11(11):1031-1035(2009)

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$ 80.00
Cat# BP17004c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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