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RGS11 Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | O94810 |
|---|---|
| Clone Names | 100517239 |
| Gene ID | 8786 |
|---|---|
| Other Names | Regulator of G-protein signaling 11, RGS11, RGS11 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | RGS11 |
|---|---|
| Function | Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. |
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Provided below are standard protocols that you may find useful for product applications.
Background
The protein encoded by this gene belongs to the RGS(regulator of G protein signaling) family. Members of the RGSfamily act as GTPase-activating proteins on the alpha subunits ofheterotrimeric, signal-transducing G proteins. This proteininhibits signal transduction by increasing the GTPase activity of Gprotein alpha subunits, thereby driving them into their inactiveGDP-bound form. Alternative splicing occurs at this locus and twotranscript variants encoding distinct isoforms have beenidentified.
References
Wang, J., et al. Carcinogenesis 31(10):1755-1761(2010)Liu, C.Y., et al. Carcinogenesis 31(7):1259-1263(2010)Saleem, Y., et al. Biochem. Biophys. Res. Commun. 386(1):65-70(2009)Martin, J., et al. Nature 432(7020):988-994(2004)Sierra, D.A., et al. Genomics 79(2):177-185(2002)
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