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LIN9 Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q5TKA1 |
|---|---|
| Clone Names | 110617116 |
| Gene ID | 286826 |
|---|---|
| Other Names | Protein lin-9 homolog, HuLin-9, hLin-9, Beta subunit-associated regulator of apoptosis, TUDOR gene similar protein, Type I interferon receptor beta chain-associated protein, pRB-associated protein, LIN9, BARA, TGS |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | LIN9 |
|---|---|
| Synonyms | BARA, TGS |
| Function | Acts as a tumor suppressor. Inhibits DNA synthesis. Its ability to inhibit oncogenic transformation is mediated through its association with RB1. Plays a role in the expression of genes required for the G1/S transition. |
| Cellular Location | Nucleus, nucleoplasm. Note=Found in perinucleolar structures. Associated with chromatin |
| Tissue Location | Expressed in thymus and testis. |
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Provided below are standard protocols that you may find useful for product applications.
Background
LIN9 acts as a tumor suppressor. Inhibits DNA synthesis. Its ability to inhibit oncogenic transformation is mediated through its association with RB1. Plays a role in the expression of genes required for the G1/S transition.
References
Rose, J. Phd, et al. Mol. Med. (2010) In press :Arking, D.E., et al. PLoS ONE 5 (3), E9879 (2010) :Pilkinton, M., et al. Oncogene 26(54):7535-7543(2007)Osterloh, L., et al. EMBO J. 26(1):144-157(2007)Pilkinton, M., et al. J. Biol. Chem. 282(1):168-175(2007)
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