|Other Names||Condensin-2 complex subunit G2, Chromosome-associated protein G2, CAP-G2, hCAP-G2, Leucine zipper protein 5, Non-SMC condensin II complex subunit G2, NCAPG2, LUZP5|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Regulatory subunit of the condensin-2 complex, a complex which establishes mitotic chromosome architecture and is involved in physical rigidity of the chromatid axis.|
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Provided below are standard protocols that you may find useful for product applications.
Condensin complexes I and II play essential roles inmitotic chromosome assembly and segregation. Both condensinscontain 2 invariant structural maintenance of chromosome (SMC)subunits, SMC2 (MIM 605576) and SMC4 (MIM 605575), but they containdifferent sets of non-SMC subunits. NCAPG2 is 1 of 3 non-SMCsubunits that define condensin II (Ono et al., 2003 [PubMed14532007]).
Wood, J.L., et al. J. Biol. Chem. 283(43):29586-29592(2008)Nousiainen, M., et al. Proc. Natl. Acad. Sci. U.S.A. 103(14):5391-5396(2006)Nousiainen, M., et al. Proc. Natl. Acad. Sci. U.S.A. 103(14):5391-5396(2006)Smith, E.D., et al. Mol. Cell. Biol. 24(3):1168-1173(2004)Ono, T., et al. Cell 115(1):109-121(2003)
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