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CCL27 Antibody (C-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q9Y4X3
Clone Names 100623202
Additional Information
Gene ID 10850
Other Names C-C motif chemokine 27, CC chemokine ILC, Cutaneous T-cell-attracting chemokine, CTACK, ESkine, IL-11 R-alpha-locus chemokine, Skinkine, Small-inducible cytokine A27, CCL27, ILC, SCYA27
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name CCL27
Synonyms ILC, SCYA27
Function Chemotactic factor that attracts skin-associated memory T- lymphocytes. May play a role in mediating homing of lymphocytes to cutaneous sites. Binds to CCR10.
Cellular Location Secreted {ECO:0000250|UniProtKB:Q9Z1X0}.
Tissue Location Testis, thymus, placenta, ovary and skin.
Research Areas
Citations (0)
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Background

This gene is one of several CC cytokine genes clustered onthe p-arm of chromosome 9. Cytokines are a family of secretedproteins involved in immunoregulatory and inflammatory processes.The CC cytokines are proteins characterized by two adjacentcysteines. The protein encoded by this gene is chemotactic forskin-associated memory T lymphocytes. This cytokine may also play arole in mediating homing of lymphocytes to cutaneous sites. Itspecifically binds to chemokine receptor 10 (CCR10). Studies of asimilar murine protein indicate that these protein-receptorinteractions have a pivotal role in T cell-mediated skininflammation.

References

Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Schuurhof, A., et al. Pediatr. Pulmonol. 45(6):608-613(2010)Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)Siezen, C.L., et al. Pediatr. Infect. Dis. J. 28(4):333-335(2009)Narbutt, J., et al. Mediators Inflamm. 2009, 269541 (2009) :

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$ 277.78
Cat# BP17080b
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