ARF5 Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | P84085 |
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Clone Names | 100712090 |
Gene ID | 381 |
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Other Names | ADP-ribosylation factor 5, ARF5 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | ARF5 |
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Function | GTP-binding protein involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus. |
Cellular Location | Golgi apparatus. Cytoplasm, perinuclear region. Membrane; Lipid-anchor. Golgi apparatus, trans-Golgi network membrane {ECO:0000250|UniProtKB:P84084}; Lipid-anchor {ECO:0000250|UniProtKB:P84084} |
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Provided below are standard protocols that you may find useful for product applications.
Background
ADP-ribosylation factor 5 (ARF5) is a member of the humanARF gene family. These genes encode small guaninenucleotide-binding proteins that stimulate theADP-ribosyltransferase activity of cholera toxin and play a role invesicular trafficking and as activators of phospholipase D. Thegene products include 6 ARF proteins and 11 ARF-like proteins andconstitute 1 family of the RAS superfamily. The ARF proteins arecategorized as class I (ARF1, ARF2,and ARF3), class II (ARF4 andARF5) and class III (ARF6). The members of each class share acommon gene organization. The ARF5 gene spans approximately 3.2kbof genomic DNA and contains six exons and five introns. [providedby RefSeq].
References
Shiba, T., et al. Proc. Natl. Acad. Sci. U.S.A. 103(42):15416-15421(2006)Austin, C., et al. Biochemistry 41(14):4669-4677(2002)Shin, O.H., et al. Biochemistry 40(36):10846-10852(2001)Nevrivy, D.J., et al. J. Biol. Chem. 275(22):16827-16836(2000)Kondo, A., et al. Mol. Biol. Cell 11(4):1315-1327(2000)
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