|Other Names||Promotilin, Motilin, Motilin-associated peptide, MAP, MLN|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Plays an important role in the regulation of interdigestive gastrointestinal motility and indirectly causes rhythmic contraction of duodenal and colonic smooth muscle.|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a small peptide hormone that is secretedby cells of the small intestine to regulate gastrointestinalcontractions and motility. Proteolytic processing of the secretedprotein produces the mature peptide and a byproduct referred to asmotilin-associated peptide (MAP). Three transcript variantsencoding different preproprotein isoforms but the same maturepeptide have been found for this gene.
Kestenbaum, B., et al. J. Am. Soc. Nephrol. 21(7):1223-1232(2010)Sjolund, K., et al. Peptides 31(6):1109-1112(2010)Barcellos, L.F., et al. PLoS Genet. 5 (10), E1000696 (2009) :Cotsapas, C., et al. Hum. Mol. Genet. 18(18):3502-3507(2009)Zhang, Z.H., et al. World J. Gastroenterol. 14(25):4077-4081(2008)
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