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MLN Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P12872 |
|---|---|
| Clone Names | 100712111 |
| Gene ID | 4295 |
|---|---|
| Other Names | Promotilin, Motilin, Motilin-associated peptide, MAP, MLN |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | MLN |
|---|---|
| Function | Plays an important role in the regulation of interdigestive gastrointestinal motility and indirectly causes rhythmic contraction of duodenal and colonic smooth muscle. |
| Cellular Location | Secreted. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a small peptide hormone that is secretedby cells of the small intestine to regulate gastrointestinalcontractions and motility. Proteolytic processing of the secretedprotein produces the mature peptide and a byproduct referred to asmotilin-associated peptide (MAP). Three transcript variantsencoding different preproprotein isoforms but the same maturepeptide have been found for this gene.
References
Kestenbaum, B., et al. J. Am. Soc. Nephrol. 21(7):1223-1232(2010)Sjolund, K., et al. Peptides 31(6):1109-1112(2010)Barcellos, L.F., et al. PLoS Genet. 5 (10), E1000696 (2009) :Cotsapas, C., et al. Hum. Mol. Genet. 18(18):3502-3507(2009)Zhang, Z.H., et al. World J. Gastroenterol. 14(25):4077-4081(2008)
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