DNAJA2 Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | O60884 |
---|---|
Clone Names | 100712267 |
Gene ID | 10294 |
---|---|
Other Names | DnaJ homolog subfamily A member 2, Cell cycle progression restoration gene 3 protein, Dnj3, Dj3, HIRA-interacting protein 4, Renal carcinoma antigen NY-REN-14, DNAJA2, CPR3, HIRIP4 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | DNAJA2 |
---|---|
Synonyms | CPR3, HIRIP4 |
Function | Co-chaperone of Hsc70. Stimulates ATP hydrolysis and the folding of unfolded proteins mediated by HSPA1A/B (in vitro) (PubMed:24318877). |
Cellular Location | Membrane; Lipid-anchor |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
The protein encoded by this gene belongs to theevolutionarily conserved DNAJ/HSP40 family of proteins, whichregulate molecular chaperone activity by stimulating ATPaseactivity. DNAJ proteins may have up to 3 distinct domains: aconserved 70-amino acid J domain, usually at the N terminus; aglycine/phenylalanine (G/F)-rich region; and a cysteine-rich domaincontaining 4 motifs resembling a zinc finger domain. The product ofthis gene works as a cochaperone of Hsp70s in protein folding andmitochondrial protein import in vitro.
References
Walker, V.E., et al. J. Biol. Chem. 285(5):3319-3329(2010)Rosales-Hernandez, A., et al. Cell Stress Chaperones 14(1):71-82(2009)Tzankov, S., et al. J. Biol. Chem. 283(40):27100-27109(2008)Lamesch, P., et al. Genomics 89(3):307-315(2007)Olsen, J.V., et al. Cell 127(3):635-648(2006)
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.