|Other Names||T-cell receptor-associated transmembrane adapter 1, T-cell receptor-interacting molecule, TRIM, pp29/30, TRAT1, TCRIM|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Stabilizes the TCR (T-cell antigen receptor)/CD3 complex at the surface of T-cells.|
|Cellular Location||Cell membrane; Single-pass type III membrane protein|
|Tissue Location||Strongly expressed in thymus, and to a lesser extent in spleen, lymph node and peripheral blood lymphocytes Present in T-cells and NK cells, but not B-cells (at protein level).|
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Provided below are standard protocols that you may find useful for product applications.
TRAT1 stabilizes the TCR (T-cell antigen receptor)/CD3 complex at the surface of T-cells.
Jarvis, L.B., et al. Hum. Immunol. 69(11):687-695(2008)Tedoldi, S., et al. Blood 107(1):213-221(2006)Koyasu, S. Nat. Immunol. 4(4):313-319(2003)Kirchgessner, H., et al. J. Exp. Med. 193(11):1269-1284(2001)Zhang, W., et al. Semin. Immunol. 12(1):35-41(2000)
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