|Other Names||Transmembrane protein 175, TMEM175|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Organelle-specific potassium channel specifically responsible for potassium conductance in endosomes and lysosomes. Forms a potassium-permeable leak-like channel, which regulates lumenal pH stability and is required for autophagosome-lysosome fusion. Constitutes the major lysosomal potassium channel.|
|Cellular Location||Endosome membrane; Multi-pass membrane protein. Lysosome membrane; Multi-pass membrane protein|
|Tissue Location||Widely expressed.|
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Provided below are standard protocols that you may find useful for product applications.
TMEM175 (transmembrane protein 175) is a hypothetical protein found in Chromosome 4.
Gerhard, D.S., et al. Genome Res. 14 (10B), 2121-2127 (2004) :Ota, T., et al. Nat. Genet. 36(1):40-45(2004)
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