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AKIRIN2 Antibody (C-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q53H80
Clone Names 110617105
Peptide ID 110617105
Additional Information
Gene ID 55122
Other Names Akirin-2, AKIRIN2, C6orf166
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name AKIRIN2
Synonyms C6orf166
Function Required for the innate immune response. Downstream effector of the Toll-like receptor (TLR), TNF and IL-1 beta signaling pathways leading to the production of IL-6. Forms a complex with YWHAB that acts to repress transcription of DUSP1 (By similarity).
Cellular Location Nucleus.
Tissue Location Widely expressed with the highest expression in peripheral blood leukocytes.
Research Areas
Citations (0)

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Background

Required for the innate immune response. Downstream effector of the Toll-like receptor (TLR), TNF and IL-1 beta signaling pathways leading to the production of IL-6. Forms a complex with YWHAB that acts to repress transcription of DUSP1 (By similarity).

References

Komiya, Y., et al. J. Biol. Chem. 283(27):18753-18764(2008)Goto, A., et al. Nat. Immunol. 9(1):97-104(2008)Levy, D., et al. BMC Med. Genet. 8 SUPPL 1, S3 (2007) :Vasan, R.S., et al. BMC Med. Genet. 8 SUPPL 1, S2 (2007) :Olsen, J.V., et al. Cell 127(3):635-648(2006)

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$ 80.00
Cat# BP17163b
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