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TNNI3 Antibody (Center) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession P19429
Clone Names 100427007
Peptide ID 100427007
Additional Information
Gene ID 7137
Other Names Troponin I, cardiac muscle, Cardiac troponin I, TNNI3, TNNC1
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name TNNI3
Synonyms TNNC1
Function Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.
Research Areas
Citations (0)

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Background

Troponin I (TnI), along with troponin T (TnT) and troponinC (TnC), is one of 3 subunits that form the troponin complex of thethin filaments of striated muscle. TnI is the inhibitory subunit;blocking actin-myosin interactions and thereby mediating striatedmuscle relaxation. The TnI subfamily contains three genes:TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, andTnI-cardiac. This gene encodes the TnI-cardiac protein and isexclusively expressed in cardiac muscle tissues. Mutations in thisgene cause familial hypertrophic cardiomyopathy type 7 (CMH7) andfamilial restrictive cardiomyopathy (RCM).

References

Millat, G., et al. Clin. Chim. Acta 411 (23-24), 1983-1991 (2010) :Murakami, C., et al. Leg Med (Tokyo) 12(6):280-283(2010)Millat, G., et al. Eur J Med Genet 53(5):261-267(2010)Di Chiara, A., et al. J Cardiovasc Med (Hagerstown) 11(8):587-592(2010)Napan, S., et al. Coron. Artery Dis. 21(5):261-265(2010)

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$ 80.00
Cat# BP17180c
Size:
Quantity:
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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