|Other Names||Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1, 6-mannosyltransferase, Asparagine-linked glycosylation protein 12 homolog, hALG12, Dolichyl-P-Man:Man(7)GlcNAc(2)-PP-dolichyl-alpha-1, 6-mannosyltransferase, Mannosyltransferase ALG12 homolog, Membrane protein SB87, ALG12|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Adds the eighth mannose residue in an alpha-1,6 linkage onto the dolichol-PP-oligosaccharide precursor (dolichol-PP- Man(7)GlcNAc(2)) required for protein glycosylation.|
|Cellular Location||Endoplasmic reticulum membrane; Multi-pass membrane protein|
|Tissue Location||Expressed in fibroblasts.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
This gene encodes a member of the glycosyltransferase 22family. The encoded protein catalyzes the addition of the eighthmannose residue in an alpha-1,6 linkage onto thedolichol-PP-oligosaccharide precursor (dolichol-PP-Man(7)GlcNAc(2))required for protein glycosylation. Mutations in this gene havebeen associated with congenital disorder of glycosylation type Ig(CDG-Ig)characterized by abnormal N-glycosylation. [provided byRefSeq].
Wan, D., et al. Proc. Natl. Acad. Sci. U.S.A. 101(44):15724-15729(2004)Jaeken, J., et al. Curr. Opin. Pediatr. 16(4):434-439(2004)Jaeken, J. J. Inherit. Metab. Dis. 27(3):423-426(2004)Zdebska, E., et al. Pediatr. Res. 54(2):224-229(2003)Thiel, C., et al. Biochem. J. 367 (PT 1), 195-201 (2002) :
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.