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SGCA Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q16586
Clone Names 100623250
Peptide ID 100623250
Additional Information
Gene ID 6442
Other Names Alpha-sarcoglycan, Alpha-SG, 50 kDa dystrophin-associated glycoprotein, 50DAG, Adhalin, Dystroglycan-2, SGCA, ADL, DAG2
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms ADL, DAG2
Function Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.
Cellular Location Cell membrane, sarcolemma; Single-pass type I membrane protein. Cytoplasm, cytoskeleton
Tissue Location Most strongly expressed in skeletal muscle. Also expressed in cardiac muscle and, at much lower levels, in lung. In the fetus, most abundant in cardiac muscle and, at lower levels, in lung. Also detected in liver and kidney. Not expressed in brain
Research Areas
Citations (0)

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This gene encodes a component of thedystrophin-glycoprotein complex (DGC), which is critical to thestability of muscle fiber membranes and to the linking of the actincytoskeleton to the extracellular matrix. Its expression is thoughtto be restricted to striated muscle. Mutations in this gene resultin type 2D autosomal recessive limb-girdle muscular dystrophy.Multiple transcript variants encoding different isoforms have beenfound for this gene.


Mendell, J.R., et al. Ann. Neurol. 68(5):629-638(2010)Fernandez, K., et al. Am. J. Pathol. 176(1):416-434(2010)Klinge, L., et al. Neuromuscul. Disord. 18(12):934-941(2008)Delgado-Olguin, P., et al. Biochim. Biophys. Acta 1779(1):74-80(2008)Rafii, M.S., et al. J. Cell. Physiol. 209(2):439-447(2006)

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$ 80.00
Cat# BP17217c
Availability: In Stock
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