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KIF3B Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | O15066 |
|---|---|
| Clone Names | 100712131 |
| Gene ID | 9371 |
|---|---|
| Other Names | Kinesin-like protein KIF3B, HH0048, Microtubule plus end-directed kinesin motor 3B, Kinesin-like protein KIF3B, N-terminally processed, KIF3B, KIAA0359 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | KIF3B |
|---|---|
| Synonyms | KIAA0359 |
| Function | Microtubule-based molecular motor that transport intracellular cargos, such as vesicles, organelles and protein complexes. Uses ATP hydrolysis to generate force to bind and move along the microtubule (By similarity). Plays a role in cilia formation (PubMed:32386558). Involved in photoreceptor integrity and opsin trafficking in rod photoreceptors (PubMed:32386558). Transports vesicles containing N-methyl-D-aspartate (NMDA) receptor subunit GRIN2A into neuronal dendrites (By similarity). |
| Cellular Location | Cytoplasm, cytoskeleton. Cell projection, cilium {ECO:0000250|UniProtKB:Q61771}. Cell projection, dendritic spine {ECO:0000250|UniProtKB:Q61771} |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
The protein encoded by this gene acts as a heterodimerwith kinesin family member 3A to aid in chromosome movement duringmitosis and meiosis. The encoded protein is a plus end-directedmicrotubule motor and can interact with the SMC3 subunit of thecohesin complex. In addition, the encoded protein may be involvedin the intracellular movement of membranous organelles. Thisprotein and kinesin family member 3A form the kinesin II subfamilyof the kinesin superfamily.
References
Reed, A.A., et al. Am. J. Physiol. Renal Physiol. 298 (2), F365-F380 (2010) :Keil, R., et al. J. Cell. Sci. 122 (PT 8), 1174-1183 (2009) :Schonteich, E., et al. J. Cell. Sci. 121 (PT 22), 3824-3833 (2008) :Wu, Y., et al. Hum. Mol. Genet. 15(22):3280-3292(2006)Haraguchi, K., et al. J. Biol. Chem. 281(7):4094-4099(2006)
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