|Other Names||Kinesin-like protein KIF3B, HH0048, Microtubule plus end-directed kinesin motor 3B, Kinesin-like protein KIF3B, N-terminally processed, KIF3B, KIAA0359|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Involved in tethering the chromosomes to the spindle pole and in chromosome movement. Microtubule-based anterograde translocator for membranous organelles. Plus end-directed microtubule sliding activity in vitro (By similarity).|
|Cellular Location||Cytoplasm, cytoskeleton.|
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Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene acts as a heterodimerwith kinesin family member 3A to aid in chromosome movement duringmitosis and meiosis. The encoded protein is a plus end-directedmicrotubule motor and can interact with the SMC3 subunit of thecohesin complex. In addition, the encoded protein may be involvedin the intracellular movement of membranous organelles. Thisprotein and kinesin family member 3A form the kinesin II subfamilyof the kinesin superfamily.
Reed, A.A., et al. Am. J. Physiol. Renal Physiol. 298 (2), F365-F380 (2010) :Keil, R., et al. J. Cell. Sci. 122 (PT 8), 1174-1183 (2009) :Schonteich, E., et al. J. Cell. Sci. 121 (PT 22), 3824-3833 (2008) :Wu, Y., et al. Hum. Mol. Genet. 15(22):3280-3292(2006)Haraguchi, K., et al. J. Biol. Chem. 281(7):4094-4099(2006)
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