|Other Names||Uronyl 2-sulfotransferase, 282-, UST, DS2ST|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Sulfotransferase that catalyzes the transfer of sulfate to the position 2 of uronyl residues. Has mainly activity toward iduronyl residues in dermatan sulfate, and weaker activity toward glucuronyl residues of chondroitin sulfate. Has no activity toward desulfated N-resulfated heparin.|
|Cellular Location||Golgi apparatus membrane; Single-pass type II membrane protein|
|Tissue Location||Widely expressed.|
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Provided below are standard protocols that you may find useful for product applications.
Uronyl 2-sulfotransferase transfers sulfate to the2-position of uronyl residues, such as iduronyl residues indermatan sulfate and glucuronyl residues in chondroitin sulfate(Kobayashi et al., 1999 [PubMed 10187838]).
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Uher, R., et al. Am J Psychiatry 167(5):555-564(2010)Trynka, G., et al. Gut 58(8):1078-1083(2009)Xu, D., et al. J. Biol. Chem. 282(11):8356-8367(2007)Ohtake, S., et al. J. Biol. Chem. 280(47):39115-39123(2005)
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