|Other Names||STE20/SPS1-related proline-alanine-rich protein kinase, Ste-20-related kinase, Serine/threonine-protein kinase 39, Stk39, Spak|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||May act as a mediator of stress-activated signals. Mediates the inhibiton of SLC4A4, SLC26A6 as well as CFTR activities by the WNK scaffolds, probably through phosphorylation (PubMed:21317537, PubMed:23542070).|
|Cellular Location||Cytoplasm. Nucleus. Note=Nucleus when caspase-cleaved.|
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Provided below are standard protocols that you may find useful for product applications.
Stk39 may act as a mediator of stress-activated signals.
Yang, S.S., et al. J. Am. Soc. Nephrol. 21(11):1868-1877(2010)Gagnon, K.B., et al. Am. J. Physiol., Cell Physiol. 299 (3), C614-C620 (2010) :Sid, B., et al. J. Physiol. (Lond.) 588 (PT 13), 2315-2328 (2010) :Reiche, J., et al. Mol. Cell. Biol. 30(12):3027-3037(2010)Hengl, T., et al. Proc. Natl. Acad. Sci. U.S.A. 107(13):6052-6057(2010)
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