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C14orf166 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9Y224 |
|---|---|
| Clone Names | 110717018 |
| Gene ID | 51637 |
|---|---|
| Other Names | UPF0568 protein C14orf166, CLE7 homolog, CLE, C14orf166 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | RTRAF (HGNC:23169) |
|---|---|
| Function | RNA-binding protein involved in modulation of mRNA transcription by Polymerase II (PubMed:16950395). Component of the tRNA-splicing ligase complex and is required for tRNA ligation (PubMed:24870230). May be required for RNA transport (PubMed:24608264). |
| Cellular Location | Nucleus. Cytoplasm, cytosol. Cytoplasm, perinuclear region. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=May localize at the centrosome during mitosis (PubMed:15147888). Shuttles between the cytosol and the nucleus: enters into the nucleus in case of active transcription while it accumulates in cytosol when transcription level is low (PubMed:24608264). |
| Tissue Location | Widely expressed. Expressed at high level in heart and skeletal muscle. Expressed at intermediate level in liver, pancreas, fetal brain and fetal lung. Weakly expressed in adult brain, adult lung, placenta, fetal liver and fetal kidney. Overexpressed in many brain tumors. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Belongs to the UPF0568 family.
References
Cui, Y., et al. Int. J. Cancer 124(7):1614-1621(2009)Andersen, J.S., et al. Nature 433(7021):77-83(2005)Howng, S.L., et al. FEBS Lett. 566 (1-3), 162-168 (2004) :Huarte, M., et al. J. Virol. 75(18):8597-8604(2001)Dawson, S.J., et al. J. Infect. 24(3):317-320(1992)
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