|Other Names||Calcium-binding protein 4, CaBP4, CABP4|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Involved in normal synaptic function through regulation of Ca(2+) influx and neurotransmitter release in photoreceptor synaptic terminals and in auditory transmission. Modulator of CACNA1D and CACNA1F, suppressing the calcium-dependent inactivation and shifting the activation range to more hyperpolarized voltages (By similarity).|
|Cellular Location||Cytoplasm. Note=Found in rod spherules and cone pedicles of the presynapses from both types of photoreceptors.|
|Tissue Location||Expressed in retina and in the inner hair cells (IHC) of the cochlea|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
This gene encodes a member of the CABP family of calciumbinding protein characterized by four EF-hand motifs. Mutations inthis gene are associated with congenital stationary night blindnesstype 2B.
Aldahmesh, M.A., et al. Mol. Vis. 16, 207-212 (2010) :Littink, K.W., et al. Invest. Ophthalmol. Vis. Sci. 50(5):2344-2350(2009)Zeitz, C., et al. Am. J. Hum. Genet. 79(4):657-667(2006)Taylor, T.D., et al. Nature 440(7083):497-500(2006)Haeseleer, F., et al. Nat. Neurosci. 7(10):1079-1087(2004)
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.