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KCTD13 Antibody (C-term) Blocking Peptide

Synthetic peptide

     
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  • CITATIONS
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Product Information
Primary Accession Q8WZ19
Clone Names 110717087
Peptide ID 110717087
Additional Information
Gene ID 253980
Other Names BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1, hBACURD1, BTB/POZ domain-containing protein KCTD13, Polymerase delta-interacting protein 1, TNFAIP1-like protein, KCTD13, BACURD1, PDIP1, POLDIP1
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name KCTD13
Synonyms BACURD1, PDIP1, POLDIP1
Function Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved in regulation of cytoskeleton structure. The BCR(BACURD1) E3 ubiquitin ligase complex mediates the ubiquitination of RHOA, leading to its degradation by the proteasome, thereby regulating the actin cytoskeleton and cell migration.
Cellular Location Nucleus.
Tissue Location Expressed in a wide variety of tissues.
Research Areas
Citations (0)

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Background

Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved in regulation of cytoskeleton structure. The BCR(BACURD1) E3 ubiquitin ligase complex mediates the ubiquitination of RHOA, leading to its degradation by the proteasome, thereby regulating the actin cytoskeleton and cell migration.

References

Chen, Y., et al. Mol. Cell 35(6):841-855(2009)Tomaru, T., et al. Endocrinology 147(1):377-388(2006)Zhou, J., et al. J. Exp. Zoolog. Part A Comp. Exp. Biol. 303(3):227-240(2005)Wan, D., et al. Proc. Natl. Acad. Sci. U.S.A. 101(44):15724-15729(2004)Kutsenko, A.S., et al. Nucleic Acids Res. 30(14):3163-3170(2002)

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$ 80.00
Cat# BP17375b
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