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PDE6D Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession O43924
Clone Names 100528226
Peptide ID 100528226
Additional Information
Gene ID 5147
Other Names Retinal rod rhodopsin-sensitive cGMP 3', 5'-cyclic phosphodiesterase subunit delta, GMP-PDE delta, Protein p17, PDE6D, PDED
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name PDE6D
Synonyms PDED
Function Promotes the release of prenylated target proteins from cellular membranes (PubMed:9712853). Modulates the activity of prenylated or palmitoylated Ras family members by regulating their subcellular location (PubMed:22002721, PubMed:23698361). Required for normal ciliary targeting of farnesylated target proteins, such as INPP5E (PubMed:24166846). Modulates the subcellular location of target proteins by acting as a GTP specific dissociation inhibitor (GDI) (By similarity). Increases the affinity of ARL3 for GTP by several orders of magnitude. Stabilizes ARL3-GTP by decreasing the nucleotide dissociation rate (By similarity).
Cellular Location Cytoplasm, cytosol. Cytoplasmic vesicle membrane; Peripheral membrane protein. Cytoplasm, cytoskeleton, cilium basal body
Tissue Location Widely expressed. Detected in various tissues including spleen, prostate gland, testis, ovary, small intestine, colon, retina, and peripheral blood.
Research Areas
Citations (0)

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Acts as a GTP specific dissociation inhibitor (GDI). Increases the affinity of ARL3 for GTP by several orders of magnitude and does so by decreasing the nucleotide dissociation rate. Stabilizes Arl3-GTP by decreasing the nucleotide dissociation.


Gudbjartsson, D.F., et al. Nat. Genet. 40(5):609-615(2008)Wilson, S.J., et al. J. Biol. Chem. 281(17):11780-11786(2006)Stelzl, U., et al. Cell 122(6):957-968(2005)Hanzal-Bayer, M., et al. EMBO J. 21(9):2095-2106(2002)Nancy, V., et al. J. Biol. Chem. 277(17):15076-15084(2002)

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$ 80.00
Cat# BP17384c
Availability: In Stock
Bulk Size
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