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ARL6IP5 Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession O75915
Clone Names 100623090
Peptide ID 100623090
Additional Information
Gene ID 10550
Other Names PRA1 family protein 3, ADP-ribosylation factor-like protein 6-interacting protein 5, ARL-6-interacting protein 5, Aip-5, Cytoskeleton-related vitamin A-responsive protein, Dermal papilla-derived protein 11, GTRAP3-18, Glutamate transporter EAAC1-interacting protein, JM5, Prenylated Rab acceptor protein 2, Protein JWa, Putative MAPK-activating protein PM27, ARL6IP5, DERP11, JWA, PRA2, PRAF3
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name ARL6IP5
Synonyms DERP11, JWA, PRA2, PRAF3
Function Regulates intracellular concentrations of taurine and glutamate. Negatively modulates SLC1A1/EAAC1 glutamate transport activity by decreasing its affinity for glutamate in a PKC activity-dependent manner. May be involved in membrane traffic.
Cellular Location Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q9ES40}; Multi-pass membrane protein. Cell membrane {ECO:0000250|UniProtKB:Q9ES40}; Multi-pass membrane protein. Cytoplasm {ECO:0000250|UniProtKB:Q9ES40}. Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:Q9ES40}. Note=Also exists as a soluble form in the cytoplasm. Associated with microtubules {ECO:0000250|UniProtKB:Q9ES40}
Research Areas
Citations (0)

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Expression of this gene is affected by vitamin A. Theencoded protein of this gene may be associated with thecytoskeleton. A similar protein in rats may play a role in theregulation of cell differentiation. The rat protein binds andinhibits the cell membrane glutamate transporter EAAC1. Theexpression of the rat gene is upregulated by retinoic acid, whichresults in a specific reduction in EAAC1-mediated glutamatetransport.


Edenberg, H.J., et al. Alcohol. Clin. Exp. Res. 34(5):840-852(2010)Akiduki, S., et al. J. Biol. Chem. 283(46):31323-31332(2008)Ruggiero, A.M., et al. J. Biol. Chem. 283(10):6175-6183(2008)Watabe, M., et al. Mol. Pharmacol. 72(5):1103-1110(2007)Zhu, Y.J., et al. J. Toxicol. Environ. Health Part A 70(11):895-900(2007)

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$ 80.00
Cat# BP17402c
Availability: In Stock
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