|Other Names||Leukocyte-specific transcript 1 protein, Protein B144, LST1, B144|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Possible role in modulating immune responses. Induces morphological changes including production of filopodia and microspikes when overexpressed in a variety of cell types and may be involved in dendritic cell maturation. Isoform 1 and isoform 2 have an inhibitory effect on lymphocyte proliferation.|
|Cellular Location||Membrane; Single-pass membrane protein. Golgi apparatus membrane; Single-pass membrane protein Endomembrane system; Single-pass membrane protein. Note=Also detected in a perinuclear region corresponding to the localization of the Golgi apparatus and throughout the cytoplasm|
|Tissue Location||Expressed in lung, tonsil, thymus, placenta, kidney, fetal spleen, fetal liver and brain|
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Possible role in modulating immune responses. Induces morphological changes including production of filopodia and microspikes when overexpressed in a variety of cell types and may be involved in dendritic cell maturation. Isoform 1 and isoform 2 have an inhibitory effect on lymphocyte proliferation.
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Man, M., et al. J Clin Pharmacol 50(8):929-940(2010)Rojas, J., et al. Ophthalmology (2010) In press :Wang, X., et al. PLoS ONE 5 (8), E11934 (2010) :Ovsyannikova, I.G., et al. PLoS ONE 5 (7), E11806 (2010) :
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