|Other Names||Tripartite motif-containing protein 16, Estrogen-responsive B box protein, TRIM16, EBBP|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||May play a role in the regulation of keratinocyte differentiation.|
|Tissue Location||Highest levels found in testis, ovary, small intestine, colon, placenta, heart, skeletal muscle and mammary gland. More highly expressed in the fetus than in the corresponding adult tissues. Expressed in basal keratinocytes|
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Provided below are standard protocols that you may find useful for product applications.
This gene was identified as an estrogen and anti-estrogenregulated gene in epithelial cells stably expressing estrogenreceptor. The protein encoded by this gene contains two B boxdomains and a coiled-coiled region that are characteristic of the Bbox zinc finger protein family. The proteins of this family havebeen reported to be involved in a variety of biological processesincluding cell growth, differentiation and pathogenesis. Expressionof this gene was detected in most tissues. Its function, however,has not yet been determined.
Raif, A., et al. Cancer Lett. 277(1):82-90(2009)Olsen, J.V., et al. Cell 127(3):635-648(2006)Munding, C., et al. Cell Death Differ. 13(11):1938-1949(2006)Cheung, B.B., et al. J. Biol. Chem. 281(26):18246-18256(2006)Gwinn, M.R., et al. Environ. Health Perspect. 113(8):1046-1051(2005)
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