|Other Names||Interleukin-20 receptor subunit alpha, IL-20 receptor subunit alpha, IL-20R-alpha, IL-20RA, Cytokine receptor class-II member 8, Cytokine receptor family 2 member 8, CRF2-8, IL-20R1, ZcytoR7, IL20RA|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||The IL20RA/IL20RB dimer is a receptor for IL19, IL20 and IL24. The IL20RA/IL10RB dimer is a receptor for IL26.|
|Cellular Location||Membrane; Single-pass type I membrane protein|
|Tissue Location||Widely expressed with highest levels in skin and testis and high levels in brain. Highly expressed in psoriatic skin.|
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Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene is a receptor forinterleukin 20 (IL20), a cytokine that may be involved in epidermalfunction. The receptor of IL20 is a heterodimeric receptor complexconsisting of this protein and interleukin 20 receptor beta(IL20B). This gene and IL20B are highly expressed in skin. Theexpression of both genes is found to be upregulated in Psoriasis.
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Davila, S., et al. Genes Immun. 11(3):232-238(2010)Kingo, K., et al. J. Dermatol. Sci. 57(1):71-73(2010)Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)Zhu, H., et al. HBPD INT 8(4):402-406(2009)
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