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GGT6 Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q6P531 |
|---|---|
| Clone Names | 110729091 |
| Gene ID | 124975 |
|---|---|
| Other Names | Gamma-glutamyltransferase 6, GGT 6, Gamma-glutamyltranspeptidase 6, Glutathione hydrolase 6, Gamma-glutamyltransferase 6 heavy chain, Gamma-glutamyltransferase 6 light chain, GGT6 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | GGT6 (HGNC:26891) |
|---|---|
| Function | Hydrolyzes and transfers gamma-glutamyl moieties from glutathione and other gamma-glutamyl compounds to acceptors. |
| Cellular Location | Membrane {ECO:0000250|UniProtKB:P19440}; Single- pass type II membrane protein {ECO:0000250|UniProtKB:P07314} |
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Provided below are standard protocols that you may find useful for product applications.
Background
GGT6 belongs to the gamma-glutamyltransferase (GGT; EC2.3.2.2) gene family. GGT is a membrane-bound extracellular enzymethat cleaves gamma-glutamyl peptide bonds in glutathione and otherpeptides and transfers the gamma-glutamyl moiety to acceptors. GGTis also key to glutathione homeostasis because it providessubstrates for glutathione synthesis (Heisterkamp et al., 2008[PubMed 18357469]).
References
Heisterkamp, N., et al. Hum. Genet. 123(4):321-332(2008)
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