|Other Names||Gamma-glutamyltransferase 6, GGT 6, Gamma-glutamyltranspeptidase 6, Glutathione hydrolase 6, Gamma-glutamyltransferase 6 heavy chain, Gamma-glutamyltransferase 6 light chain, GGT6|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Cleaves glutathione conjugates.|
|Cellular Location||Membrane; Single-pass type II membrane protein|
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Provided below are standard protocols that you may find useful for product applications.
GGT6 belongs to the gamma-glutamyltransferase (GGT; EC184.108.40.206) gene family. GGT is a membrane-bound extracellular enzymethat cleaves gamma-glutamyl peptide bonds in glutathione and otherpeptides and transfers the gamma-glutamyl moiety to acceptors. GGTis also key to glutathione homeostasis because it providessubstrates for glutathione synthesis (Heisterkamp et al., 2008[PubMed 18357469]).
Heisterkamp, N., et al. Hum. Genet. 123(4):321-332(2008)
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