|Other Names||Cell adhesion molecule 2, Immunoglobulin superfamily member 4D, IgSF4D, Nectin-like protein 3, NECL-3, Synaptic cell adhesion molecule 2, SynCAM 2, CADM2, IGSF4D, NECL3|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Adhesion molecule that engages in homo- and heterophilic interactions with the other nectin-like family members, leading to cell aggregation. Important for synapse organization, providing regulated trans-synaptic adhesion. Preferentially binds to oligodendrocytes.|
|Cellular Location||Cell membrane; Single-pass type I membrane protein Cell junction, synapse. Cell projection, axon. Note=Found in the axoplasm of myelinated axons|
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Provided below are standard protocols that you may find useful for product applications.
Members of the large immunoglobulin (Ig) superfamily, suchas IGSF4D, have diverse roles in extracellular recognition andintercellular adhesion (Biederer, 2006 [PubMed 16311015]).[suppliedby OMIM].
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Festen, E.A., et al. Am. J. Gastroenterol. 105(2):395-402(2010)Biederer, T. Genomics 87(1):139-150(2006)
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