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CADM2 Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q8N3J6 |
|---|---|
| Clone Names | 110808093 |
| Gene ID | 253559 |
|---|---|
| Other Names | Cell adhesion molecule 2, Immunoglobulin superfamily member 4D, IgSF4D, Nectin-like protein 3, NECL-3, Synaptic cell adhesion molecule 2, SynCAM 2, CADM2, IGSF4D, NECL3 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | CADM2 |
|---|---|
| Synonyms | IGSF4D, NECL3 |
| Function | Adhesion molecule that engages in homo- and heterophilic interactions with the other nectin-like family members, leading to cell aggregation. Important for synapse organization, providing regulated trans-synaptic adhesion. Preferentially binds to oligodendrocytes. |
| Cellular Location | Cell membrane; Single-pass type I membrane protein Synapse. Cell projection, axon. Note=Found in the axoplasm of myelinated axons |
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Provided below are standard protocols that you may find useful for product applications.
Background
Members of the large immunoglobulin (Ig) superfamily, suchas IGSF4D, have diverse roles in extracellular recognition andintercellular adhesion (Biederer, 2006 [PubMed 16311015]).[suppliedby OMIM].
References
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Festen, E.A., et al. Am. J. Gastroenterol. 105(2):395-402(2010)Biederer, T. Genomics 87(1):139-150(2006)
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