|Other Names||Cytokine receptor-like factor 3, Cytokine receptor-like molecule 9, CREME-9, Cytokine receptor-related protein 4, Type I cytokine receptor-like factor p48, CRLF3, CREME9, CRLM9, CYTOR4, P48|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Synonyms||CREME9, CRLM9, CYTOR4, P48|
|Function||May play a role in the negative regulation of cell cycle progression.|
|Cellular Location||Cytoplasm. Note=The EGFP- and MYC-tagged protein has been shown to be cytoplasmic.|
|Tissue Location||Expressed in several embryonic and adult tissues, including adult and fetal brain, liver, spleen and pancreas. Expressed in adult, but not fetal kidney. Expressed in skin and squamous cell carcinoma (SCC) and in several other cancer types. Also detected in lesion actinic keratosis (AK)|
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Provided below are standard protocols that you may find useful for product applications.
CRLF3 (Cytokine receptor-like factor 3) contains one fibronectin type-III domain. It is expressed in skin and squamous cell carcinoma (SCC) and in lesion actinic keratosis (AK).
Johnatty, S.E., et al. PLoS Genet. 6 (7), E1001016 (2010) :Zhao, J., et al. BMC Med. Genet. 11, 96 (2010) :Yang, F., et al. Int. J. Biochem. Cell Biol. 41(11):2240-2250(2009)Visser, R., et al. Am. J. Med. Genet. A 149A (4), 806-808 (2009) :Gudbjartsson, D.F., et al. Nat. Genet. 40(5):609-615(2008)
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