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TPM2 Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P07951
Clone Names 90121042
Peptide ID 90121042
Additional Information
Gene ID 7169
Other Names Tropomyosin beta chain, Beta-tropomyosin, Tropomyosin-2, TPM2, TMSB
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name TPM2
Synonyms TMSB
Function Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments. The non-muscle isoform may have a role in agonist-mediated receptor internalization (By similarity).
Cellular Location Cytoplasm, cytoskeleton.
Tissue Location Present in primary breast cancer tissue, absent from normal breast tissue. {ECO:0000269|Ref.10}
Research Areas
Citations (0)

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This gene encodes beta-tropomyosin, a member of the actinfilament binding protein family, and mainly expressed in slow, type1 muscle fibers. Mutations in this gene can alter the expression ofother sarcomeric tropomyosin proteins, and cause cap disease,nemaline myopathy and distal arthrogryposis syndromes.Alternatively spliced transcript variants encoding differentisoforms have been found for this gene.


Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Martins-de-Souza, D., et al. J Psychiatr Res 44(14):989-991(2010)Assinder, S.J., et al. Mol. Carcinog. 49(6):525-531(2010)Ochala, J., et al. Proc. Natl. Acad. Sci. U.S.A. 107(21):9807-9812(2010)Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)

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$ 80.00
Cat# BP17546b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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