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WDR4 Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P57081
Clone Names 100603158
Peptide ID 100603158
Additional Information
Gene ID 10785
Other Names tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4 {ECO:0000255|HAMAP-Rule:MF_03056}, WD repeat-containing protein 4 {ECO:0000255|HAMAP-Rule:MF_03056}, WDR4 {ECO:0000255|HAMAP-Rule:MF_03056}
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name WDR4 {ECO:0000255|HAMAP-Rule:MF_03056}
Function Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit.
Cellular Location Nucleus {ECO:0000255|HAMAP-Rule:MF_03056, ECO:0000269|PubMed:15861136}
Research Areas
Citations (0)

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This gene encodes a member of the WD repeat proteinfamily. WD repeats are minimally conserved regions of approximately40 amino acids typically bracketed by gly-his and trp-asp (GH-WD),which may facilitate formation of heterotrimeric or multiproteincomplexes. Members of this family are involved in a variety ofcellular processes, including cell cycle progression, signaltransduction, apoptosis, and gene regulation. This gene is excludedas a candidate for a form of nonsyndromic deafness (DFNB10), but isstill a candidate for other disorders mapped to 21q22.3 as well asfor the development of Down syndrome phenotypes. Two transcriptvariants encoding the same protein have been found for this gene.


Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)Olsen, J.V., et al. Cell 127(3):635-648(2006)Hu, Y.H., et al. BMC Genomics 7, 155 (2006) :Cartlidge, R.A., et al. EMBO J. 24(9):1696-1705(2005)Alexandrov, A., et al. RNA 8(10):1253-1266(2002)

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$ 80.00
Cat# BP17552c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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