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EVI2B Antibody (Center) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession P34910
Clone Names 110617047
Peptide ID 110617047
Additional Information
Other Names Protein EVI2B, Ecotropic viral integration site 2B protein homolog, EVI-2B, CD361, EVI2B, EVDB
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name EVI2B
Synonyms EVDB
Cellular Location Membrane; Single-pass type I membrane protein
Tissue Location Bone marrow, peripheral blood mononuclear cells, fibroblasts and Epstein-Barr virus-transformed lymphoblastoid cell lines EMBL; M60830; AAA35816.1; -; Genomic_DNA EMBL; AK297087; BAH12493.1; -; mRNA EMBL; AC134669; -; NOT_ANNOTATED_CDS; Genomic_DNA CCDS; CCDS11266.1; -. [P34910-1] PIR; A38445; A38445 RefSeq; NP_006486.3; NM_006495.3. [P34910-1] RefSeq; XP_005258003.1; XM_005257946.3. [P34910-2] UniGene; Hs.5509; - ProteinModelPortal; P34910; - STRING; 9606.ENSP00000333779; - iPTMnet; P34910; - PhosphoSitePlus; P34910; - SwissPalm; P34910; - BioMuta; EVI2B; - DMDM; 281185464; - EPD; P34910; - MaxQB; P34910; - PaxDb; P34910; - PeptideAtlas; P34910; - PRIDE; P34910; - DNASU; 2124; - Ensembl; ENST00000330927; ENSP00000333779; ENSG00000185862. [P34910-1] Ensembl; ENST00000577894; ENSP00000462682; ENSG00000185862. [P34910-1] GeneID; 2124; - KEGG; hsa:2124; - UCSC; uc002hgk.3; human. [P34910-1] CTD; 2124; - DisGeNET; 2124; - GeneCards; EVI2B; - H-InvDB; HIX0013696; - HGNC; HGNC:3500; EVI2B HPA; HPA007436; - HPA; HPA053383; - MIM; 158381; gene neXtProt; NX_P34910; - OpenTargets; ENSG00000185862; - PharmGKB; PA27914; - eggNOG; ENOG410IVU1; Eukaryota eggNOG; ENOG41118NF; LUCA GeneTree; ENSGT00390000009142; - HOGENOM; HOG000285986; - HOVERGEN; HBG051514; - InParanoid; P34910; - KO; K16854; - OMA; HTSAGQP; - OrthoDB; EOG091G0GGD; - PhylomeDB; P34910; - TreeFam; TF336167; - BioCyc; ZFISH:G66-33877-MONOMER; - GeneWiki; EVI2B; - GenomeRNAi; 2124; - PRO; PR:P34910; - Proteomes; UP000005640; Chromosome 17 Bgee; ENSG00000185862; - CleanEx; HS_EVI2B; - Genevisible; P34910; HS GO; GO:0005887; C:integral component of plasma membrane; TAS:ProtInc InterPro; IPR033239; EVI2B PANTHER; PTHR15384; PTHR15384; 1 ProDom; PD140898; PD140898; 1 1: Evidence at protein level; Alternative splicing; Complete proteome; Glycoprotein; Membrane; Phosphoprotein; Polymorphism; Proto-oncogene; Reference proteome; Signal; Transmembrane; Transmembrane helix SIGNAL 1 21 CHAIN 22 448 Protein EVI2B /FTId=PRO_0000021213 TOPO_DOM 22 202 Extracellular. TRANSMEM 203 226 Helical. TOPO_DOM 227 448 Cytoplasmic. MOD_RES 249 249 Phosphothreonine {ECO:0000250|UniProtKB:Q8VD58} MOD_RES 268 268 Phosphoserine MOD_RES 271 271 Phosphoserine MOD_RES 278 278 Phosphoserine {ECO:0000250|UniProtKB:Q8VD58} MOD_RES 294 294 Phosphoserine CARBOHYD 16 16 N-linked (GlcNAc...). CARBOHYD 50 50 N-linked (GlcNAc...). CARBOHYD 114 114 N-linked (GlcNAc...). VAR_SEQ 1 1 M -> MLFRYAEKITRKYSEM (in isoform 2) /FTId=VSP_056461 VARIANT 53 53 G -> R (in dbSNP:rs9903564) /FTId=VAR_056871 CONFLICT 37 37 F -> Y (in Ref. 1; AAA35816) SEQUENCE 448 AA; 48666 MW; 5BF2DC46798577E3 CRC64; MDPKYFILIL FCGHLNNTFF SKTETITTEK QSQPTLFTSS MSQVLANSQN TTGNPLGQPT QFSDTFSGQS ISPAKVTAGQ PTPAVYTSSE KPEAHTSAGQ PLAYNTKQPT PIANTSSQQA VFTSARQLPS ARTSTTQPPK SFVYTFTQQS SSVQIPSRKQ ITVHNPSTQP TSTVKNSPRS TPGFILDTTS NKQTPQKNNY NSIAAILIGV LLTSMLVAII IIVLWKCLRK PVLNDQNWAG RSPFADGETP DICMDNIREN EISTKRTSII SLTPWKPSKS TLLADDLEIK LFESSENIED SNNPKTEKIK DQVNGTSEDS ADGSTVGTAV SSSDDADLPP PPPLLDLEGQ ESNQSDKPTM TIVSPLPNDS TSLPPSLDCL NQDCGDHKSE IIQSFPPLDS LNLPLPPVDF MKNQEDSNLE IQCQEFSIPP NSDQDLNESL PPPPAELL
Research Areas
Citations (0)

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Background

EVI2B (Ecotropic viral integration site 2B) may function as an oncogene in retrovirus-induced myeloid tumors and may have a role in leukemogenesis.

References

Douglas, J., et al. Nat. Genet. 39(8):963-965(2007)Xu, G., et al. Genomics 13(3):537-542(1992)Wallace, M.R., et al. Nature 353(6347):864-866(1991)Cawthon, R.M., et al. Genomics 9(3):446-460(1991)Viskochil, D., et al. Mol. Cell. Biol. 11(2):906-912(1991)

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$ 80.00
Cat# BP17567c
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