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RGL4 Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q8IZJ4
Clone Names 110726186
Peptide ID 110726186
Additional Information
Gene ID 266747
Other Names Ral-GDS-related protein, hRGR, Ral guanine nucleotide dissociation stimulator-like 4, RalGDS-like 4, RGL4, RGR
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name RGL4
Synonyms RGR
Cellular Location Cytoplasmic vesicle.
Research Areas
Citations (0)

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Ral GDS (Ral guanine nucleotide dissociation stimulator) is a guanine nucleotide exchange factor (GEF) that activates Ral and is implicated in oncogenic Ras-induced cell transformation. RGL4 (ral guanine nucleotide dissociation stimulator-like 4), also known as Rgr, is a 473 amino acid protein that localizes to the cytoplasmic vesicle of cells. Belonging to the GEF family of proteins, RGL4 induces phosphorylation of ERKs, p38 and JNK kinases, and it increases the levels of GTP bound forms of Ral and Ras. Ras activation is crucial for the transforming activity of RGL4. Due to its similarity to Ral GDS, RGL4 may be implicated in carcinogenesis.


Hernandez-Munoz, I., et al. Cancer Res. 63(14):4188-4195(2003)Hernandez-Munoz, I., et al. Oncogene 19(23):2745-2757(2000)Dunham, I., et al. Nature 402(6761):489-495(1999)D'Adamo, D.R., et al. Oncogene 14(11):1295-1305(1997)

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$ 80.00
Cat# BP17597a
Availability: In Stock
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