Foundational characteristics of cancer include proliferation, angiogenesis, migration, evasion of apoptosis, and cellular immortality. Find key markers for these cellular processes and antibodies to detect them.
The SUMOplot™ Analysis Program predicts and scores sumoylation sites in your protein. SUMOylation is a post-translational modification involved in various cellular processes, such as nuclear-cytosolic transport, transcriptional regulation, apoptosis, protein stability, response to stress, and progression through the cell cycle.
The Autophagy Receptor Motif Plotter predicts and scores autophagy receptor binding sites in your protein. Identifying proteins connected to this pathway is critical to understanding the role of autophagy in physiological as well as pathological processes such as development, differentiation, neurodegenerative diseases, stress, infection, and cancer.
BTN3A3 Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | O00478 |
|---|---|
| Clone Names | 110717017 |
| Gene ID | 10384 |
|---|---|
| Other Names | Butyrophilin subfamily 3 member A3, BTN3A3, BTF3 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | BTN3A3 |
|---|---|
| Synonyms | BTF3 |
| Function | Plays a role in T-cell responses in the adaptive immune response. |
| Cellular Location | Cell membrane; Single-pass type I membrane protein |
| Tissue Location | Detected in peripheral blood mononuclear cells and in T-cells (at protein level). Detected in spleen and lymphocytes |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
The butyrophilin (BTN) genes are a group of majorhistocompatibility complex (MHC)-associated genes that encode typeI membrane proteins with 2 extracellular immunoglobulin (Ig)domains and an intracellular B30.2 (PRYSPRY) domain. Threesubfamilies of human BTN genes are located in the MHC class Iregion: the single-copy BTN1A1 gene (MIM 601610) and the BTN2(e.g., BTN2A1; MIM 613590) and BTN3 (e.g., BNT3A3) genes, whichhave undergone tandem duplication, resulting in 3 copies of each(summary by Smith et al., 2010 [PubMed 20208008]).[supplied byOMIM].
References
Smith, I.A., et al. J. Immunol. 184(7):3514-3525(2010)Zhang, Z., et al. Protein Sci. 13(10):2819-2824(2004)Rhodes, D.A., et al. Genomics 71(3):351-362(2001)Henry, J., et al. Immunol. Today 20(6):285-288(1999)Ruddy, D.A., et al. Genome Res. 7(5):441-456(1997)
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.
Ordering Information
Other Products
Shipping Information
