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MAFG Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession O15525
Clone Names 100712055
Peptide ID 100712055
Additional Information
Gene ID 4097
Other Names Transcription factor MafG, V-maf musculoaponeurotic fibrosarcoma oncogene homolog G, hMAF, MAFG
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Function Since they lack a putative transactivation domain, the small Mafs behave as transcriptional repressors when they dimerize among themselves. However, they seem to serve as transcriptional activators by dimerizing with other (usually larger) basic-zipper proteins and recruiting them to specific DNA-binding sites. Small Maf proteins heterodimerize with Fos and may act as competitive repressors of the NF-E2 transcription factor. Transcription factor, component of erythroid-specific transcription factor NF- E2. Activates globin gene expression when associated with NF-E2. May be involved in signal transduction of extracellular H(+) (By similarity).
Cellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00978, ECO:0000269|PubMed:11154691}
Tissue Location Highly expressed in skeletal muscle. Also expressed in heart and brain
Research Areas
Citations (0)

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Globin gene expression is regulated through nuclear factorerythroid-2 (NFE2) elements located in enhancer-like locus controlregions positioned many kb upstream of alpha- and beta-geneclusters (summarized by Blank et al., 1997 [PubMed 9166829]). NFE2DNA-binding activity consists of a heterodimer containing aubiquitous small Maf protein (MafF, MIM 604877; MafG; or MafK, MIM600197) and the tissue-restricted protein p45 NFE2 (MIM 601490).Both subunits are members of the activator protein-1-likesuperfamily of basic leucine zipper (bZIP) proteins (see MIM165160).


Wang, X., et al. PLoS ONE 5 (8), E11934 (2010) :Berg, D.T., et al. J. Biol. Chem. 282(51):36837-36844(2007)Yamamoto, T., et al. Genes Cells 11(6):575-591(2006)Stelzl, U., et al. Cell 122(6):957-968(2005)Tramier, M., et al. Biophys. J. 83(6):3570-3577(2002)

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$ 80.00
Cat# BP17800a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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