Register or Login
  • All
  • Uniprot Id
  • Catalog #
  • Peptide Sequence
>   home   >   Products   >   Peptides   >   Blocking Peptides   >   DR1 Antibody (Center) Blocking Peptide   

DR1 Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q01658
Clone Names 100517033
Peptide ID 100517033
Additional Information
Gene ID 1810
Other Names Protein Dr1, Down-regulator of transcription 1, Negative cofactor 2-beta, NC2-beta, TATA-binding protein-associated phosphoprotein, DR1
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name DR1
Function The association of the DR1/DRAP1 heterodimer with TBP results in a functional repression of both activated and basal transcription of class II genes. This interaction precludes the formation of a transcription-competent complex by inhibiting the association of TFIIA and/or TFIIB with TBP. Can bind to DNA on its own. Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4.
Cellular Location Nucleus.
Research Areas
Citations (0)

Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.

Submit your citation using an Abgent antibody to, and receive a free "I Love Antibodies" mug.


This gene encodes a TBP- (TATA box-binding protein)associated phosphoprotein that represses both basal and activatedlevels of transcription. The encoded protein is phosphorylated invivo and this phosphorylation affects its interaction with TBP.This protein contains a histone fold motif at the amino terminus, aTBP-binding domain, and a glutamine- and alanine-rich region. Thebinding of DR1 repressor complexes to TBP-promoter complexes mayestablish a mechanism in which an altered DNA conformation,together with the formation of higher order complexes, inhibits theassembly of the preinitiation complex and controls the rate of RNApolymerase II transcription.


Corneveaux, J.J., et al. Hum. Mol. Genet. 19(16):3295-3301(2010)Kantidakis, T., et al. Nucleic Acids Res. 38(4):1228-1239(2010)Albert, T.K., et al. Genome Biol. 11 (3), R33 (2010) :Kahle, J., et al. J. Biol. Chem. 284(14):9382-9393(2009)Wang, Y.L., et al. J. Biol. Chem. 283(49):33808-33815(2008)

Abgent welcomes feedback from its customers.

If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.

If you have any additional inquiries please email technical services at

$ 80.00
Cat# BP17826c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
Request Quote Here

Ordering Information

United States
AlbaniaAustraliaAustriaBelgiumBosnia & HerzegovinaBrazilBulgariaCanadaChinaCroatiaCyprusCzech RepublicDenmarkEstoniaFinlandFranceGermanyGreeceHong KongHungaryIcelandIndiaIndonesiaIrelandIsraelItalyJapanKoreaLatviaLithuaniaLuxembourgMacedoniaMalaysiaMaltaNetherlandsNew ZealandNorwayPakistanPolandPortugalRomaniaSerbiaSingaporeSlovakiaSloveniaSouth AfricaSpainSwedenSwitzerlandTaiwanTurkeyUnited KingdomUnited StatesVietnamOthers
Abgent, Inc.
(888) 735-7227 / (858) 622-0099
(858) 622-0609

Shipping Information

Domestic orders (in stock items)
Shipped out the same day. Orders placed after 1 PM (PST) will ship out the next business day.
International orders
Contact your local distributors
Santa Cruz Alternative
Terms & Conditions