PROM2 Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q8N271 |
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Clone Names | 110808246 |
Gene ID | 150696 |
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Other Names | Prominin-2, PROM-2, Prominin-like protein 2, hPROML2, PROM2, PROML2 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | PROM2 |
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Synonyms | PROML2 |
Cellular Location | Apical cell membrane; Multi-pass membrane protein. Basolateral cell membrane; Multi-pass membrane protein. Cell projection, microvillus membrane; Multi-pass membrane protein. Cell projection, cilium membrane; Multi-pass membrane protein. Note=Colocalizes with PROM1 Associates with membrane in a cholesterol-dependent manner. Localizes to the apical and basolateral membranes of epithelial cells (By similarity). |
Tissue Location | Present in saliva within small membrane particles (at protein level). Expressed in kidney, prostate, trachea, esophagus, salivary gland, thyroid gland, mammary gland adrenal gland, placenta, stomach, spinal cord and liver. In submucosal tumor, expressed in spindle-shaped or stellate stromal cells. Expressed in prostate cancer cell lines. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a member of the prominin family ofpentaspan membrane glycoproteins. The encoded protein localizes tobasal epithelial cells and may be involved in the organization ofplasma membrane microdomains. Alternative splicing results inmultiple transcript variants.
References
Jaszai, J., et al. Histochem. Cell Biol. 133(5):527-539(2010)Yao, J., et al. Oncol. Rep. 22(4):781-787(2009)Jaszai, J., et al. Histochem. Cell Biol. 130(4):749-759(2008)Fargeas, C.A., et al. J. Biol. Chem. 278(10):8586-8596(2003)
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