ALG5 Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q9Y673 |
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Clone Names | 90819098 |
Gene ID | 29880 |
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Other Names | Dolichyl-phosphate beta-glucosyltransferase, DolP-glucosyltransferase, Asparagine-linked glycosylation protein 5 homolog, ALG5 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | ALG5 |
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Function | Required for the assembly of lipid-linked oligosaccharides in kidney epithelial cells, and protein N-glycosylation. Required for polycystin-1 (PKD1) glycosylation and maturation. |
Cellular Location | Endoplasmic reticulum membrane; Single-pass type II membrane protein |
Tissue Location | Expressed in pancreas, placenta, liver, heart, brain, kidney, skeletal muscle, and lung |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a member of the glycosyltransferase 2family. The encoded protein participates in glucosylation of theoligomannose core in N-linked glycosylation of proteins. Theaddition of glucose residues to the oligomannose core is necessaryto ensure substrate recognition, and therefore, effectual transferof the oligomannose core to the nascent glycoproteins. Multipletranscript variants encoding different isoforms have been found forthis gene.
References
Imbach, T., et al. Proc. Natl. Acad. Sci. U.S.A. 96(12):6982-6987(1999)
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