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ANAPC4 Antibody (Center) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q9UJX5
Clone Names 90819113
Peptide ID 90819113
Additional Information
Gene ID 29945
Other Names Anaphase-promoting complex subunit 4, APC4, Cyclosome subunit 4, ANAPC4, APC4
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name ANAPC4
Synonyms APC4
Function Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
Research Areas
Citations (0)

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Background

A large protein complex, termed the anaphase-promotingcomplex (APC), or the cyclosome, promotes metaphase-anaphasetransition by ubiquitinating its specific substrates such asmitotic cyclins and anaphase inhibitor, which are subsequentlydegraded by the 26S proteasome. Biochemical studies have shown thatthe vertebrate APC contains eight subunits. The composition of theAPC is highly conserved in organisms from yeast to humans. Theexact function of this gene product is not known. [provided byRefSeq].

References

Wasch, R., et al. Oncogene 29(1):1-10(2010)Jin, L., et al. Cell 133(4):653-665(2008)Nature 447(7145):661-678(2007)Dube, P., et al. Mol. Cell 20(6):867-879(2005)Listovsky, T., et al. EMBO J. 23(7):1619-1626(2004)

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$ 80.00
Cat# BP17878c
Size:
Quantity:
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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