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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   ADCY9 Antibody (C-term) Blocking Peptide   

ADCY9 Antibody (C-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession O60503
Clone Names 90819061
Peptide ID 90819061
Additional Information
Gene ID 115
Other Names Adenylate cyclase type 9, ATP pyrophosphate-lyase 9, Adenylate cyclase type IX, Adenylyl cyclase 9, ADCY9, KIAA0520
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name ADCY9
Synonyms KIAA0520
Function Adenylyl cyclase that catalyzes the formation of the signaling molecule cAMP in response to activation of G protein- coupled receptors (PubMed:9628827, PubMed:12972952, PubMed:15879435, PubMed:10987815). Contributes to signaling cascades activated by CRH (corticotropin-releasing factor), corticosteroids and beta-adrenergic receptors (PubMed:9628827).
Cellular Location Cell membrane; Multi-pass membrane protein
Tissue Location Detected in skeletal muscle, pancreas, lung, heart, kidney, liver, brain and placenta (PubMed:9628827, PubMed:10987815). Expressed in multiple cells of the lung, with expression highest in airway smooth muscle (PubMed:12972952)
Research Areas
Citations (0)

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Background

Adenylate cyclase is a membrane bound enzyme thatcatalyses the formation of cyclic AMP from ATP. It is regulated bya family of G protein-coupled receptors, protein kinases, andcalcium. The type 9 adenylyl cyclase is a widely distributedadenylyl cyclase, and it is stimulated by beta-adrenergic receptoractivation but is insensitive to forskolin, calcium, andsomatostatin.

References

Wojcik, C., et al. Am. J. Med. Genet. A 152A (2), 479-483 (2010) :Olsen, J.V., et al. Cell 127(3):635-648(2006)Tantisira, K.G., et al. Hum. Mol. Genet. 14(12):1671-1677(2005)Cumbay, M.G., et al. J. Pharmacol. Exp. Ther. 310(1):108-115(2004)Small, K.M., et al. Pharmacogenetics 13(9):535-541(2003)

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$ 80.00
Cat# BP17882b
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