|Other Names||Paraneoplastic antigen Ma3, PNMA3, MA3|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Cellular Location||Nucleus, nucleolus.|
|Tissue Location||Expressed at high levels in the brain and testis. Expressed at lower levels in the heart, trachea and kidney.|
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This gene is a member of the paraneoplastic antigen MA(PNMA) gene family, whose protein products share homology withretroviral Gag proteins. They are highly expressed in the brain andalso in a range of tumors associated with serious neurologicalphenotypes. PMID:16407312 reports the presence of a functional -1ribosomal frameshift signal (consisting of a heptanucleotide shiftmotif followed 3' by a pseudoknot structure) in this gene, however,the frame-shifted product has not been characterized. [provided byRefSeq].
Wills, N.M., et al. J. Biol. Chem. 281(11):7082-7088(2006)Schuller, M., et al. J. Neuroimmunol. 169 (1-2), 172-176 (2005) :Rosenfeld, M.R., et al. Ann. Neurol. 50(3):339-348(2001)
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