DHRS11 Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q6UWP2 |
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Clone Names | 110729075 |
Gene ID | 79154 |
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Other Names | Dehydrogenase/reductase SDR family member 11, 1---, DHRS11 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | DHRS11 |
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Synonyms | SDR24C1 {ECO:0000303|PubMed:19027726} |
Function | Catalyzes the conversion of the 17-keto group of estrone, 4- and 5-androstenes and 5-alpha-androstanes into their 17-beta- hydroxyl metabolites and the conversion of the 3-keto group of 3-, 3,17- and 3,20- diketosteroids into their 3-hydroxyl metabolites. Exhibits reductive 3-beta-hydroxysteroid dehydrogenase activity toward 5-beta-androstanes, 5-beta-pregnanes, 4-pregnenes and bile acids. May also reduce endogenous and exogenous alpha-dicarbonyl compounds and xenobiotic alicyclic ketones. |
Cellular Location | Secreted. |
Tissue Location | Isoform 1: Ubiquitously expressed, with highest levels in testis, small intestine, colon, kidney, brain and heart Isoform 3: Expressed in brain, heart and skeletal muscle |
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Provided below are standard protocols that you may find useful for product applications.
Background
The function of this protein remains unknown.
References
Persson, B., et al. Chem. Biol. Interact. 178 (1-3), 94-98 (2009) :Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)
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