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FBXL8 Antibody (N-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q96CD0
Clone Names 110808139
Peptide ID 110808139
Additional Information
Gene ID 55336
Other Names F-box/LRR-repeat protein 8, F-box and leucine-rich repeat protein 8, F-box protein FBL8, FBXL8, FBL8
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name FBXL8
Synonyms FBL8
Function Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex.
Research Areas
Citations (0)

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Background

This gene encodes a member of the F-box protein familywhich is characterized by an approximately 40 amino acid motif, theF-box. The F-box proteins constitute one of the four subunits ofthe ubiquitin protein ligase complex called SCFs(SKP1-cullin-F-box), which function in phosphorylation-dependentubiquitination. The F-box proteins are divided into 3 classes: Fbwscontaining WD-40 domains, Fbls containing leucine-rich repeats, andFbxs containing either different protein-protein interactionmodules or no recognizable motifs. The protein encoded by this genebelongs to the Fbls class. It shares 78% sequence identity with themouse protein.

References

Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)Lievens, S., et al. J. Proteome Res. 8(2):877-886(2009)Winston, J.T., et al. Curr. Biol. 9(20):1180-1182(1999)

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$ 80.00
Cat# BP17930a
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