|Other Names||Acid-sensing ion channel 5, ASIC5, Amiloride-sensitive cation channel 5, Human intestine Na(+) channel, HINaC, ASIC5, ACCN5, HINAC|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Cation channel that gives rise to very low constitutive currents in the absence of activation. The activated channel exhibits selectivity for sodium, and is inhibited by amiloride.|
|Cellular Location||Cell membrane; Multi-pass membrane protein|
|Tissue Location||Detected in small intestine, duodenum and jejunum. Detected at very low levels in testis and rectum|
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Provided below are standard protocols that you may find useful for product applications.
This gene belongs to the amiloride-sensitive Na+ channeland degenerin (NaC/DEG) family, members of which have beenidentified in many animal species ranging from the nematode tohuman. The amiloride-sensitive Na(+) channel encoded by this geneis primarily expressed in the small intestine, however, its exactfunction is not known.
Schaefer, L., et al. FEBS Lett. 471 (2-3), 205-210 (2000) :
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